Key Points
- Question Is adolescent cannabis consumption associated with risk of depression, anxiety, and suicidality in young adulthood?
- Findings In this systematic review and meta-analysis of 11 studies and 23,317 individuals, adolescent cannabis consumption was associated with increased risk of developing depression and suicidal behavior later in life, even in the absence of a premorbid condition. There was no association with anxiety.
- Meaning Preadolescents and adolescents should avoid using cannabis as use is associated with a significant increased risk of developing depression or suicidality in young adulthood; these findings should inform public health policy and governments to apply preventive strategies to reduce the use of cannabis among youth.
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