Henry Clay 1777 - "The Great Pacificator", U.S. Secretary of State under John Quincy Adams, three time unsuccessful candidate for president of United States. Quote: "I would rather be right than president."
- 1861 - Fort Sumter was shelled by Confederacy, starting America's Civil War.
- 1877 - A catcher's mask was used in a baseball game for the first time by James Alexander Tyng.
- 1892 - Voters in Lockport, New York, became the first in the U.S. to use voting machines.
- 1945 - U.S. President Franklin D. Roosevelt died in Warm Spring, GA. He died of a cerebral hemorrhage at the age of 63. Harry S Truman became president.
- 1955 - The University of Michigan Polio Vaccine Evaluation Center announced that the polio vaccine of Dr. Jonas Salk was "safe, effective and potent."
- 1961 - Soviet Yuri Alexeyevich Gagarin became first man to orbit the Earth.
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